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More Great Information on Cholesterol Monitoring:
Cholesterol - What should you know about. by Dr. Sarah Albert
Cholesterol is oily in nature but is not the same as fat. It is an essential molecule for making cell membranes, steroid hormones, nerve sheaths, and much more. The liver makes most of the cholesterol in the body and the rest comes from the diet. Too much cholesterol in the blood is known as hypercholesterolemia.rnThis leads to clogged arteries, which causes heart attack, stroke, loss of circulation in the limbs, and kidney failure. This process is called atherosclerosis.rnCholesterol in the blood is carried by protein particles called lipoproteins. The two most important are low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Elevated levels of LDL are usually associated with cholesterol deposits in the blood vessels, so LDL is known as âbad cholesterol.â Elevated levels ofrnHDL actually protect against heart disease by scavenging cholesterol and removing it from the arteries, so HDL is known as âgood cholesterol.â Because of this, total cholesterol is not always the best measure of cholesterol.rnHigh HDL makes the total cholesterol level look too high but is actually a good thing.rnAlthough high LDL is the best known risk factor for heart disease, low HDL is also an important risk factor.rnLow HDL occurs in weight gain, inactivity, and smoking.rnTriglycerides are often measured along with cholesterol. Triglycerides are fats floating freely in the blood. If blood with a very high triglyceride level is allowed to sit in a tube, after a while a thick whitish layer of fat will rise to the top. Triglycerides are also a risk factor for heart disease, although the reason is not as well understood as it is for cholesterol.rnAtherosclerosis can affect any artery of the body.rnWhen the arteries that supply blood to the heart muscle are blocked, a heart attack occurs. When brain arteries are blocked, this causes a stroke. Blockage in arteries in the legs can lead to gangrene, and blockage of arteries to the kidneys leads to kidney failure.rnAtherosclerosis in the aorta, the main artery coming from the heart, can cause the aorta to balloon (aortic aneurysm) and eventually rupture.rnCAUSES OF ELEVATED CHOLESTEROLrnHigh cholesterol can be inherited, but it can also develop in people without a family history of high cholesterol.rnTwo inherited conditions are familial combined hyperlipidemia (occurring in 1 in 100 individuals), and familial hypercholesterolemia (occurring in 1 in 500 people). People with these conditions are at very high risk of premature heart attack and stroke, and need aggressive medical treatment. Family members should be screened for high cholesterol so they can be treated as early as possible.rnrnTREATMENTrnDiet and ExercisernThe initial step in treating high cholesterol is diet, increased physical activity, and weight loss. Reducing dietary intake of saturated fat and cholesterol is beneficial in lowering LDL cholesterol, and regular, sustained aerobic exercise increases HDL cholesterol.rnWeight loss in women may cause a decline in HDL cholesterol without much change in LDL cholesterol. Fat tissue in postmenopausal women produces estrogen, and therefore losing this source may reduce HDL cholesterol.rnrnCholesterol-Lowering MedicationsrnâStatinâ drugs (Pravastatin) inhibit the major enzyme responsible for cholesterol production in the liver. These are the most effective medications for lowering LDL cholesterol, reducing it by 25â35%. Statins are proven to reduce the chance of death from heart disease in women. They are comparatively safe and have limited side effects. They also have other benefits like increasing bone density and reducing the risk of fractures.rnBecause statins occasionally cause liver or muscle inflammation, regular blood test monitoring is required.rnOther cholesterol-lowering agents include the bile acid sequestrants: cholestyramine and colestipol. These are older drugs, and work by increasing the conversion of cholesterol to bile acids, which then leave the body in the stool. The newest drug is ezetimibe, which blocks cholesterol absorption in the intestines. rn
Doctor Sarah Albert http://www.medicinesonlineshop.com
Article Source: http://www.earticlesonline.com/Article/Cholesterol---What-should-you--know-about-/463196
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